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Posted by Diana Kemp on 1/13/2003 from 65.125.48.16:
In reply to: Additional info posted by Renee Gaines on 1/13/2003 from 216.117.218.7:
Thank you for your response. I have copies of my pathology reports and they are as follows:

8/5 - (biopsy) - breast, right, in situ and infiltrating poorly-differentiated duct carcinoma. Suspicious for angiolymphatic invasion is identified. HER2NEU (Dako Herceptest kit) 3+ strongly positive.

8/23 - (first lumpectomy) - Invasive carcinoma lumpectomy in situ and infiltrating ductal; tumor not palpable; infiltrating component elston grade is III of III. vascular invasion is not definitely identified. 10% of mass is in situ carcinoma. 3 lymph nodes negative. DCIS is extensive and represents 90% of the mass and shows pagetoid extension into larger ducts. DCIS nuclear is grade 3 of 3. Comedonecrosis is present. artichitectural pattern is comedo. Carinoma in situ extends away from in multiple foci, the invasive carcinoma.
Margins: invasive carcinoma is 7 mm from the deep margin; 8 mm frm the anterior margin; 12 mm from the lateral margin; not near the medial margin or superior margins. DCIS is 4 mm from the deep margin; 1 mm from the superior margin; 2 mm from the lateral margin. DCIS is not near the inferior, anterior or medial margins. skin is negative. surrounding breast tissue shows fibrocystic changes. pathologic stage is pT1NoMx. invasive component on core biopsy measured 0.7 cm in greatest dimension.

9/9 - (2nd lumpectomy they did not get clean margins first time). Deaccessioned case. Accessioned in error. lymph nodes negative. right breast re-excision - breast tissue with biopsy site changes, fibrocystic changes, and usual type duct hyperplasia. focal atypical lobular hyperplasia is present involving a larg duct. overlying skin with scar. no residual in situ or infiltrating carcinoma identified. immunostains for e-cadherin and smooth muscle actin were performed which support the lobular nature of the atypical focus.

I was estrogen receptor negative.

Thank you.

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